When ‘right to try’ isn’t enough: Congress wants a single ALS patient to get a therapy never tested in humans

first_img Daily reporting and analysis The most comprehensive industry coverage from a powerhouse team of reporters Subscriber-only newsletters Daily newsletters to brief you on the most important industry news of the day STAT+ Conversations Weekly opportunities to engage with our reporters and leading industry experts in live video conversations Exclusive industry events Premium access to subscriber-only networking events around the country The best reporters in the industry The most trusted and well-connected newsroom in the health care industry And much more Exclusive interviews with industry leaders, profiles, and premium tools, like our CRISPR Trackr. About the Author Reprints Washington Correspondent Nicholas Florko reports on the the intersection of politics and health policy. He is the author the newsletter “D.C. Diagnosis.” STAT+ is STAT’s premium subscription service for in-depth biotech, pharma, policy, and life science coverage and analysis. Our award-winning team covers news on Wall Street, policy developments in Washington, early science breakthroughs and clinical trial results, and health care disruption in Silicon Valley and beyond. What’s included? When ‘right to try’ isn’t enough: Congress wants a single ALS patient to get a therapy never tested in humans WASHINGTON — A family in Iowa believes the Food and Drug Administration will decide whether their only surviving daughter lives or dies, and they’ve been on a monthslong crusade to break through its bureaucracy. And they’re succeeding.Just last week, the FDA gave Jaci Hermstad, a 25-year old Iowan who is dying from a rare form of ALS, an early sign that she will receive the first dose of an experimental drug never before tested in humans. The FDA’s move, which was confirmed to STAT by Jaci’s family and doctor, is a breakthrough for the Hermstads. GET STARTED Log In | Learn More By Nicholas Florko May 31, 2019 Reprintscenter_img [email protected] Special Report Unlock this article by subscribing to STAT+ and enjoy your first 30 days free! GET STARTED @NicholasFlorko Nicholas Florko What is it? Jaci Hermstad at her relative’s ranch in Webb, Iowa. Hilary Kollasch Tags Congressdrug developmentgovernment agenciespatientspolicylast_img read more

Rakwon Visit on Chosun Central TV

Ofcom fines Vodafone UK record £4.6M for “failing customers”

first_img Vodafone UK plots open RAN research lab Related Author Previous ArticleEricsson’s incoming CEO bullish on “challenging” futureNext ArticleTelenor sees Q3 hit by India, VimpelCom Home Ofcom fines Vodafone UK record £4.6M for “failing customers” Saleha Riaz Tags Saleha joined Mobile World Live in October 2014 as a reporter and works across all e-newsletters – creating content, writing blogs and reports as well as conducting feature interviews…More Read more Ofcom completes 5G spectrum allocation Vodafone UK will be fined £4.6 million by watchdog Ofcom for “serious and sustained breaches of consumer protection rules” which the operator blamed on a complicated IT migration.This is the largest fine Ofcom has imposed on an operator.The regulator completed two investigations: one that found Vodafone failed to credit the accounts of 10,452 pay-as-you-go customers when they topped up, and the second related to failure to adhere to Ofcom’s rules of handling customer complaints.“Vodafone’s customer service agents were not given sufficiently clear guidance on what constituted a complaint, while its processes were insufficient to ensure that all complaints were appropriately escalated or dealt with in a fair, timely manner,” the watchdog said.The pay-as-you-go issue resulted in a £3.7 million fine while £925,000 was imposed “for the flaws in its complaints handling processes.”The money must be paid to Ofcom within 20 working days and will be passed on to the country’s treasury.The final figure incorporates a 7.5 per cent reduction to reflect Vodafone’s agreement to enter into a formal settlement.Lindsey Fussell, Ofcom consumer group director, said “Vodafone’s failings were serious and unacceptable, and these fines send a clear warning to all telecoms companies.”Vodafone reimbursed all pay-as-you-go customers who were impacted, except for 30 it could not identify, and made a donation of £100,000 to charity.Vodafone responseThe operator said “we deeply regret these system and process failures” and explained that the matters under investigation “were a consequence of errors during a complex IT migration which involved moving more than 28.5 million customer accounts” that began at the end of 2013 “and was the largest of its kind ever undertaken by Vodafone anywhere in the world.”It said individual customer accounts were incorrectly migrated, leading to mistakes in the customer billing data and price plan records stored on the new system.It also conducted a full internal review, overhauled management control and escalation procedures, and will invest an additional £30 million this year in customer service and training, including hiring an additional 1,000 new UK-based call centre personnel.Last summer, Ofcom imposed a £1 million fine on UK operator EE over its failure to comply with regulator rules on handling customer complaints. UK launches regulator targeting tech giants OfcomVodafone UK AddThis Sharing ButtonsShare to LinkedInLinkedInLinkedInShare to TwitterTwitterTwitterShare to FacebookFacebookFacebookShare to MoreAddThisMore 26 OCT 2016 last_img read more

Bayer Donates $15,000 and Legend® Product to Equine Canada

first_imgEquine Canada and Bayer HealthCare Animal Health are pleased to announce Bayer’s sponsorship of Equine Canada. The sponsorship is intended to support and maintain the competitiveness of Canada’s elite equestrians and equine athletes, who compete at the highest levels of Canadian and international competitions. It will also help to promote and fund the Jump Canada Emerging Rider Series, which nurtures the development of show jumping’s up and coming athletes.“We are thrilled to enter into this partnership with Equine Canada in support of Canada’s elite riders and horses,” stated Dr. Carol Jakel, DVM, Bayer HealthCare Animal Health in Toronto, ON.“In addition to the donation of funds, Bayer will also be graciously providing Legend® joint therapy to horses named to the 2011 Canadian Equestrian Team for the purposes of attending the Badminton Horse Trials, Rolex Kentucky Three Day Event and Pan American Games,” said Cheryl Tataryn, manager, Marketing and Communications with Equine Canada in Ottawa, ON.Previously, Bayer has provided Legend® to Canada’s riders and elite horse athletes for major games. “Bayer has been a huge supporter of Canadian teams so we are pleased to be able to build our relationship with Equine Canada again with monetary and Legend® product support,” said Dr. Jakel.“Equine Canada couldn’t be happier to have Bayer on board and couldn’t ask for a better sponsor,” stated Tataryn. “They’ve been around for a long time and have offered joint therapy for horses for almost two decades now. We’re happy to have them back in the saddle, so to speak, and happy to be working with them to support equestrian competition in Canada.” Tags: Equine Canada, Bayer Inc., Subscribe to the Horse Sport newsletter and get an exclusive bonus digital edition! Email* More from Horse Sport:Christilot Boylen Retires From Team SportAfter an exemplary career as one of Canada’s top Dressage riders, seven-time Olympian Christilot Boylen has announced her retirement from team competition.2020 Royal Agricultural Winter Fair CancelledFor only the second time in its history, The Royal Agricultural Winter Fair has been cancelled but plans are being made for some virtual competitions.Royal Agricultural Winter Fair Statement on 2020 EventAs the Province of Ontario starts to reopen, The Royal’s Board and staff will adhere to all recommendations put forward by government and health officials.Government Financial Assistance for Ontario FarmersOntario Equestrian has recently released this update of several financial assistance packages available, including those for farm business. Horse Sport Enews SIGN UP We’ll send you our regular newsletter and include you in our monthly giveaways. PLUS, you’ll receive our exclusive Rider Fitness digital edition with 15 exercises for more effective riding.last_img read more

Women Small Businesses Owners are Optimistic, in a Mood to Hire

In Helping His Dad With Diabetes, Young Mexican Chemist Pioneers Healthy—and Cheap—Sugar Substitute

first_img“It has so many good properties for human health, and the same flavor as sugar, but the problem was that producing it was so expensive,” said Larragoiti. “So I decided to start working on a cheaper process to make it accessible to everyone.”AMAZING: Bedridden for Years, Man Proves Experts Wrong By Inventing Surgery to Cure HimselfXylitol Made CheaperCorn is Mexico’s largest agricultural crop, and Javier has now patented a method of extracting xylitol from discarded corn cobs. Best of all, with 28 million metric tons of corn cobs generated every year in Mexico as waste, there’s no shortage of xylitol-generating fuel.Simultaneously, Larragoiti hit on the idea of how to make xylitol less expensive, while inventing a way to reuse the 28 million tons of corn cobs, substantially upgrading the traditional means of disposal: burning them.Especially in a pollution-heavy country like Mexico, reducing the amount of corn waste burned, would eliminate a portion of the carbon emissions.His business, Xilinat, buys waste from 13 local farmers, producing 1 ton of the product each year. His invention was awarded a prestigious $310,000 Chivas Venture prize award, which will enable him to industrialize his operation and scale up production 10-fold, diverting another 10 tons of corn cob from the furnace.A Better Choice for DiabeticsObesity affects a dizzying number of people worldwide. Some estimates range as high as 1 in 7 people, while type-2 diabetics and those at risk for type-2 diabetes account for 10% of the world population.MORE: Exciting New Study Says That Crops Thrive Underneath Solar Panels—and the Panels Produce More Energy While Making Farmers HealthierJavier says that sugary diets are a real problem in Mexico; a country with the world’s second-highest rate of obesity. The nation has already taxed sugary drinks as a means to combat one of the main sources of the problem.In a strange coincidence, Larragoiti’s method of extracting a sugar substitute happens to incorporate the same vegetable whose other byproduct incites the obesity epidemic in the United States: high-fructose corn syrup.“It’s kind of ironic,” Larragoiti continues in The Guardian interview, “High fructose corn syrup is just a bomb of carbs and concentrated sugar that makes a high peak of insulin. It’s many times sweeter than regular glucose. Companies use and pay less and that’s the issue.”Javier Larragoiti and Team—XilinatMORE: ‘For the First Time’, Researchers Use Healthy Stem Cells for Future Type 1 Diabetes CureHigh-fructose corn syrup is added into most processed and packaged foods and drinks, and plays a big part in the obesity epidemic in the United States, according to the CDC, which reports it affects 93 million adults.Using Corn For Sugar Substitutes—Instead of Sugar BombsHowever, with North America growing more corn than anywhere else on the planet, and with the Department of Agriculture (DOA) subsidizing its growth, the supply of corn for conversion to corn syrup is cheap and guaranteed.If Javier’s method of extracting a sugar-free substitute were implemented, the United States could convert corn fields into a more nutrient-dense row crop, shift supply away from the creation of high-fructose corn syrup, or even increase the utilization of corn for bio-ethanol, which would cause the price of different petroleum products to drop.Regardless, Larragoiti says that he is simply happy that his project has helped to keep his dad from succumbing to a sugary diet that would provoke his diabetes.“My dad is super-happy,” Larragoiti says, finishing his interview. “He uses my product every day and he’s willing not to cheat on his diet any more!”MORE: Drought-Proof ‘Cooling Houses’ Use Saltwater and Cardboard to Grow Tons of Healthy Produce in the DesertPlant Some Positivity By Sharing The Good News With Your Friends On Social Media…AddThis Sharing ButtonsShare to FacebookFacebookFacebookShare to TwitterTwitterTwitterShare to EmailEmailEmailShare to RedditRedditRedditShare to MoreAddThisMore AddThis Sharing ButtonsShare to FacebookFacebookFacebookShare to TwitterTwitterTwitterShare to EmailEmailEmailShare to RedditRedditRedditShare to MoreAddThisMoreWhen 18-year old Javier Larragoiti was told his father had been diagnosed with diabetes, the young man, who had just started studying chemical engineering at college in Mexico City, decided to dedicate his studies to finding a safe, sugar-alternative for his father.“My dad tried to use stevia and sucralose, just hated the taste, and kept cheating on his diet,” Larragoiti told The Guardian. Stevia and sucralose are both popular sugar alternatives, and many reduced-sugar products available today contain one or the other.With stevia and sucralose out of the picture, the young chemist needed to keep searching. He started dabbling with xylitol, a sweet-tasting alcohol found in birch wood but also in many fruits and vegetables. Xylitol is used in sugar-free products such as chewing gum and also in children’s medicine, but is toxic to dogs even in small amounts.last_img read more

Aaron Judge gets 10 votes for New York City mayor

first_imgHotel says PH coach apologized for ‘kikiam for breakfast’ claim MOST READ Kanter leads Knicks to easy win despite Porzingis injury In this Oct. 21, 2017, file photo, New York Yankees’ Aaron Judge waits to hit before Game 7 of baseball’s American League Championship Series against the Houston Astros in Houston. (AP Photo/Eric Christian Smith, File)NEW YORK—A unanimous winner of the AL Rookie of the Year Award and runner-up in Most Valuable Player voting, Aaron Judge also received ballots in another election: for New York City mayor.The New York Yankees right fielder was listed on 10 ballots as a write-in candidate for mayor, according to final totals released late Tuesday by the New York City Board of Elections.ADVERTISEMENT Robredo: True leaders perform well despite having ‘uninspiring’ boss PLAY LIST 02:49Robredo: True leaders perform well despite having ‘uninspiring’ boss02:42PH underwater hockey team aims to make waves in SEA Games01:44Philippines marks anniversary of massacre with calls for justice01:19Fire erupts in Barangay Tatalon in Quezon City01:07Trump talks impeachment while meeting NCAA athletes02:49World-class track facilities installed at NCC for SEA Games The Fatted Calf and Ayutthaya: New restos worth the drive to Tagaytay LATEST STORIES Judge received three votes in New York County (Manhattan and the Marble Hill section of the Bronx), four in Brooklyn, two in Queens and one in Staten Island.He was far behind Bill de Blasio, who won re-election with 713,634 votes on the Democratic line and 46,478 on the Working Families line.FEATURED STORIESSPORTSSEA Games: Biñan football stadium stands out in preparedness, completionSPORTSPrivate companies step in to help SEA Games hostingSPORTSBoxers Pacquiao, Petecio torchbearers for SEA Games openingFormer Yankees manager Joe Girardi and former Yankees captain Derek Jeter, now CEO of the Miami Marlins, got two write-in votes apiece.Kristaps Porzingis, a Latvian player on the NBA’s New York Knicks, received nine write-in votes. There was an additional vote for each of two misspelled variations of his name: Kristaps Porzinais and Kristops Porzingis. Ethel Booba on hotel’s clarification that ‘kikiam’ is ‘chicken sausage’: ‘Kung di pa pansinin, baka isipin nila ok lang’ After 30 years, Johnlu Koa still doing ‘hard-to-make’ quality breads MRT 7 on track for partial opening in 2021 ‘A complete lie:’ Drilon refutes ‘blabbermouth’ Salo’s claims Malditas save PH from shutout New York Giants quarterback Eli Manning, who was benched this week, got one vote.Sports Related Videospowered by AdSparcRead Next Don’t miss out on the latest news and information. Jordan delivers on promise: 2 Cobra choppers now in PH View commentslast_img read more

Cricket world should come forward to support Pakistan: Misbah

first_imgElated by the successful completion of their first home series in over six years, Pakistan’s Test captain Misbah-ul-Haq said rest of the cricket-playing world should also come forward to support his country now.The third and final ODI between Pakistan and Zimbabwe was abandoned last night at the Gaddafi stadium in Lahore due to a dust storm and heavy rains. But it was yet another heavy turnout of spectators.”I think the way the people have come and supported the Pakistan Cricket Board, the team and cricket throughout this series it is a strong enough message for the rest of the cricket world to give us more support now to have regular international matches in Pakistan,” Misbah told PTI.”Even I have been surprised and moved by the passion shown by the cricket fans to give a clear message to the outside world that no matter what the circumstances they love the game and want to watch teams play in Pakistan,” he said.Misbah urged the Asian teams including Sri Lanka, Bangladesh and India to offer more support to the PCB to have international matches at home.”I think Pakistan cricket has shown it has indomitable spirit and I would love to see the Asian teams playing in Pakistan, It would be a dream come true for me,” the senior batsman said.Despite increased security measures for the third ODI, once again cricket fans including women and children started lining up at least three hours before the start of the match to get into the stadium.advertisementThey filled into the stadium with most of them eager to cooperate fully with the security protocol for the match.”I have never seen such discipline from people coming to watch a cricket match it just shows that even the Pakistani people have felt the hurt of being isolated as a international venue for the last six years,” chief selector Haroon Rasheed told PTI.The turnout for the third match was impressive given that a terror attack was foiled during the second ODI when a blast took place just a kilometer away from the stadium.While Federal Information minister Pervez Rasheed claimed vigilant policemen had foiled a suicide bomb attack near the Gaddafi stadium, police officials maintained that the blast was caused by a gas cylinder in a rickshaw exploding near the stadium.A senior Pakistan Cricket Board official said despite the incident, the Zimbabwe team continued the tour and played the third match which was a big relief and success for the PCB.He said the PCB Chairman would submit a full report on the series and security protocol at the next ICC meeting.He said the PCB would now use the tour to impress upon other boards, particularly Bangladesh and Sri Lanka, to send their teams sometime next year to Pakistan.Former Test captain Rashid Latif said the ICC needs to do much more to help Pakistan have regular international matches.”I don’t think the PCB can do more to show the ICC and other boards that they are capable of organizing a series successfully and have learnt from the security mistakes made in 2009,” Latif said.last_img read more

Position Vacant – TFA Media and Communications Manager/Coordinator

first_imgAre you looking for a thrilling career in the sports industry?  Touch Football Australia (TFA) is seeking suitably qualified applicants for the position of Media and Communications Manager/Coordinator – based in our National Office in Canberra. The position will be at the Band 3 Management level or Band 3 Coordinator level pending qualifications and experience of applicants for the position.To view the Position Description, please click on the attachment below.Applications for this opportunity close at 5.00pm (AEST) on Friday, 29 July 2016. For further information or to lodge your application for this career opportunity, please email [email protected] Files160715_tfa_media_and_communications_manager_v1-0-pdfRelated LinksPosition Vacantlast_img

New hike in gas prices approved

first_imgThe rise in the international price of fuel in September forced ​​the Public Services Regulatory Authority (ARESEP) to approve another increase in fuel prices this month.Starting next week, the per-liter price of super gasoline will increase ₡30, from ₡756 to ₡786. The same increase applies to plus gasoline, which will cost ₡746 per liter, and diesel, which will increase ₡33 to ₡669 per liter.The latest increase in fuel prices was approved on Sept. 27.The new prices will go into effect when they are published in the government newspaper La Gaceta. Facebook Comments No related posts.last_img